Details, Fiction and megatomi.com

Our new Apparent+ tissue clearing technique is the sole approach that delipidates samples without modify in morphology and with small influence on structural integrity.

Megatome is a vibrating microtome made to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits high-throughput tissue sectioning with uniform floor profile, and also minimum tissue destruction and knowledge decline.

Antibodies might consider weeks to diffuse by way of just a few millimeters of tissue, by using a steep labeling gradient from floor to Main.

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SE uses a rotational electric discipline to disperse really electromobile molecules (which include antibodies or surfactant micelles) all over a porous sample with out harmful electrically billed buildings in the tissue. This allows 2-4 working day clearing of intact organs,

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Megatome is actually a novel microtome that permits for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with small tissue destruction and data reduction.

eFLASH is actually a quick tissue labeling technique which allows for uniform entire-organ staining in twenty rounds of labeling.

The SmartSPIM gentle sheet megatomi.com microscope provides unparalleled resolution and acquisition pace throughout intact tissue volumes, when its modular style means that you can improve and customise person factors.

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Leverage the Clear+ tissue clearing approach, as well as eFLASH and patented stochastic electrotransport systems, to rapidly distinct and label complete organs. Critical highlights and options include:

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